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Anti-FOXO3A Antibody (1M967)

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货号 TMAB-06135

Anti-FOXO3A Antibody (1M967) 是一种 Rabbit 抗体，靶向 FOXO3A。Anti-FOXO3A Antibody (1M967) 可用于 WB。

Anti-FOXO3A Antibody (1M967)

Anti-FOXO3A Antibody (1M967)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06135

Anti-FOXO3A Antibody (1M967) 是一种 Rabbit 抗体，靶向 FOXO3A。Anti-FOXO3A Antibody (1M967) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOXO3A Antibody (1M967) is a Rabbit antibody targeting FOXO3A. Anti-FOXO3A Antibody (1M967) can be used in WB.
Ig Type
IgG
克隆号
1M967
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytosol. Nucleus. Note=Translocates to the nucleus upon oxidative stress and in the absence of survival factors. Tissue Specificity : Ubiquitous.
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human FOXO3A protein (1-150aa)
抗原种属
Human
基因名称
FOXO3
基因ID
2309
蛋白名称
Forkhead box protein O3
Uniprot ID
O43524
功能
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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