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Anti-Siglec-9 Antibody (9T642)

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货号 TMAB-12797

Anti-Siglec-9 Antibody (9T642) 是一种 Mouse 抗体,靶向 Siglec-9。Anti-Siglec-9 Antibody (9T642) 可用于 ICC/IF,FCM。

Anti-Siglec-9 Antibody (9T642)

Anti-Siglec-9 Antibody (9T642)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12797

Anti-Siglec-9 Antibody (9T642) 是一种 Mouse 抗体,靶向 Siglec-9。Anti-Siglec-9 Antibody (9T642) 可用于 ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-Siglec-9 Antibody (9T642) is a Mouse antibody targeting Siglec-9. Anti-Siglec-9 Antibody (9T642) can be used in ICC/IF,FCM.
Ig Type
IgG1, Kappa
克隆号
9T642
反应种属
Human
应用ICC/IFFCM
推荐剂量
ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane.
组织特异性Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Two families of mammalian lectin-like adhesion molecules bind glycoconjugate ligands in a sialic acid-dependent manner: the selectins and the sialoadhesins. The sialic acid-binding immunoglobulin superfamily lectins, designated siglecs or sialoadhesins, are immunoglobulin superfamily members recognizing sialylated ligands. The common sialic acids of mammalian cells are N-acetyl-neuraminic acid (Neu5Ac) and N-glycolyl-neuraminic acid (Neu5Gc). Siglec-1 mediates local cell-cell interactions in lymphoid tissues and can be detected at contact points of macrophages with other macrophages, sinus-lining cells and reticulum cells. Siglec-7, highly expressed in monocytes and resident blood cells, but not in parenchymatous cells, mediates inhibition of natural killer cell cytotoxicity. Siglec-9 is closely homologous to Siglec-7; the gene encoding it maps to chromosome 19q13.41 in humans. It is highly expressed in peripheral blood leukocytes (but not eosinophils), liver, bone marrow, placenta and spleen. Siglec-8, a type I membrane protein, is selectively expressed on human eosinophils, basophils and mast cells, where it regulates their function and survival.
抗原信息
基因名称
SIGLEC9
基因ID
蛋白名称
Sialic acid-binding Ig-like lectin 9
功能
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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