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IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2

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货号 TMPY-05648U

别名 白介素, SGRF, P19, IL23P19, IL-23A, IL-23, IL23

IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2 is expressed in HEK293 Cells. The accession number is Q9NPF7(IL-23 alpha)&P29460(IL-12 beta).

IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2
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IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2

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货号 TMPY-05648U 别名 白介素, SGRF, P19, IL23P19, IL-23A, IL-23, IL23

IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2 is expressed in HEK293 Cells. The accession number is Q9NPF7(IL-23 alpha)&P29460(IL-12 beta).

规格价格库存数量
5 μg
¥ 987
6-8日内发货
10 μg
¥ 1,730
6-8日内发货
20 μg
¥ 2,930
5日内发货
50 μg
¥ 4,730
5日内发货
100 μg
¥ 6,830
5日内发货
200 μg
¥ 11,600
5日内发货
500 μg
¥ 23,500
5日内发货
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产品介绍

生物活性
产品描述
IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated V2 is expressed in HEK293 Cells. The accession number is Q9NPF7(IL-23 alpha)&P29460(IL-12 beta).
生物活性
Immobilized Human IL-23R, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human IL-23 alpha&IL-12 beta, His Tag with the EC50 of 0.87 μg/ml determined by ELISA.
研究背景
The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in shaping the development of antitumor or protumor immunity.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q9NPF7(IL-23 alpha)&P29460(IL-12 beta)
蛋白构建Arg20-Pro189(IL-23 alpha) & Ile23-Ser328(IL-12 beta)
蛋白纯度
> 95% as determined by Tris-Bis PAGE
蛋白性状Lyophilized powder
缓冲液Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名白介素, SGRF, P19, IL23P19, IL-23A, IL-23, IL23
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量21.7 (IL-23 alpha) & 34.7 (IL-12 beta) kDa (Predicted); 24 kDa (IL-23 alpha) and 40-50 kDa (IL-12 beta) kDa (Due to glycosylation)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

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关键词

TMPY-05648P-19P 19IL 23
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