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DNA-PKcs Protein, Human, Recombinant (GST)

Synonyms: S473K, PRKDC, p460, HYRC1, HYRC, DNPK1, DNA-PKcs, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit
货号 TMPC-00205 一键复制产品信息
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202603开学季活动

DNA-PKcs Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P78527.

DNA-PKcs Protein, Human, Recombinant (GST)

一键复制产品信息
Rating icon 还可以
202603开学季活动
货号 TMPC-00205

别名 S473K, PRKDC, p460, HYRC1, HYRC, DNPK1, DNA-PKcs, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit

DNA-PKcs Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P78527.

DNA-PKcs Protein, Human, Recombinant (GST)
规格价格库存数量
20 μg
¥ 5,930
35日内发货
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产品介绍

生物活性
产品描述
DNA-PKcs Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P78527.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景
PRKDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial for DNA double-strand break repair and V(D)J recombination. PRKDC expression was significantly increased in breast cancer tissue samples compared with NATs. High PRKDC expression was associated with higher tumor grade (P=0.001), positive lymph node metastasis (P=0.0357) and chemoresistance (P=0.0006). Furthermore, PRKDC expression was significantly correlated with OS in breast cancer patients with (0.0101) or without (P=0.0216) receiving chemotherapy. Collectively, PRKDC is a prognostic biomarker for chemoresistance in breast cancer patients.
种属
Human
表达系统
Baculovirus-Insect Cells
标签
N-GST
蛋白编号P78527
蛋白构建
Recombinant human DNAPK (3746-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
蛋白纯度
>70% as determined by SDS-PAGE.
DNA-PKcs Protein, Human, Recombinant (GST)
蛋白性状
Solution
缓冲液
Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, and 25% glycerol.
别名
S473K, PRKDC, p460, HYRC1, HYRC, DNPK1, DNA-PKcs, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit
化学信息
分子量~68 kDa
储存&溶解度
运输方式Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

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