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顶部生物活性储存和溶解信息计算器

Anti-PSGL-1/CD162 Antibody (3V438)

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产品编号 TMAY-02644

别名 selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Anti-PSGL-1/CD162 Antibody (3V438) 是一种 Mouse 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody (3V438) 可用于 ICC/IF。

Anti-PSGL-1/CD162 Antibody (3V438)

Anti-PSGL-1/CD162 Antibody (3V438)

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产品编号 TMAY-02644 别名 selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Anti-PSGL-1/CD162 Antibody (3V438) 是一种 Mouse 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody (3V438) 可用于 ICC/IF。

规格价格库存数量
100 μL
¥ 1,679
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产品介绍

生物活性
产品描述
Anti-PSGL-1/CD162 Antibody (3V438) is a Mouse antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (3V438) can be used in ICC/IF.
别名selectin P ligand, PSGL-1, PSGL1, CLA, CD162
Ig Type
Mouse IgG1
克隆号
3V438
交叉反应
Human
特异性
Human PSGL-1/CD162
验证活性
Immunofluorescence staining of SELPLG in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with mouse anti-Human SELPLG monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
应用ICC/IF
推荐剂量
ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This product is a recombinant monoclonal antibody expressed from HEK293 cells.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PSGL-1/CD162 Protein (TMPY-03531)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

PSGL 1CD-162CD 162

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4个月前
5.0
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