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Anti-SIN3A Antibody (7T227) 是一种 Rabbit 抗体,靶向 SIN3A。Anti-SIN3A Antibody (7T227) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-SIN3A Antibody (7T227) 是一种 Rabbit 抗体,靶向 SIN3A。Anti-SIN3A Antibody (7T227) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-SIN3A Antibody (7T227) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (7T227) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 7T227 |
| 反应种属 | Human,Mouse |
| 应用 | WBIHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L (By similarity). |
| 组织特异性 | Widely expressed. Highest levels in testis, lung and thymus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. |
| 免疫原 | A synthesized peptide: human SIN3A |
| 抗原种属 | Human |
| 基因名称 | SIN3A |
| 基因ID | |
| 蛋白名称 | Paired amphipathic helix protein Sin3a |
| Uniprot ID | |
| 功能 | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. |
| 分子量 | Theoretical: 145 kDa. Actual: 150 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |