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Anti-SIN3A Antibody (7T227)

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货号 TMAB-12801

Anti-SIN3A Antibody (7T227) 是一种 Rabbit 抗体,靶向 SIN3A。Anti-SIN3A Antibody (7T227) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-SIN3A Antibody (7T227)

Anti-SIN3A Antibody (7T227)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12801

Anti-SIN3A Antibody (7T227) 是一种 Rabbit 抗体,靶向 SIN3A。Anti-SIN3A Antibody (7T227) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-SIN3A Antibody (7T227) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (7T227) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
7T227
反应种属
Human,Mouse
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L (By similarity).
组织特异性Widely expressed. Highest levels in testis, lung and thymus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.
抗原信息
免疫原
A synthesized peptide: human SIN3A
抗原种属
Human
基因名称
SIN3A
基因ID
蛋白名称
Paired amphipathic helix protein Sin3a
Uniprot ID
功能
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
化学信息
分子量Theoretical: 145 kDa. Actual: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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