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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PTGER2 Antibody (6T912)

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货号 TMAB-11899

Anti-PTGER2 Antibody (6T912) 是一种 Rabbit 抗体，靶向 PTGER2。Anti-PTGER2 Antibody (6T912) 可用于 IHC-P,IF,IHC-Fr。

Anti-PTGER2 Antibody (6T912)

Anti-PTGER2 Antibody (6T912)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11899

Anti-PTGER2 Antibody (6T912) 是一种 Rabbit 抗体，靶向 PTGER2。Anti-PTGER2 Antibody (6T912) 可用于 IHC-P,IF,IHC-Fr。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTGER2 Antibody (6T912) is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Antibody (6T912) can be used in IHC-P,IF,IHC-Fr.
Ig Type
IgG
克隆号
6T912
反应种属
Human,Mouse,Rat
应用IHC-PIFIHC-Fr
推荐剂量
IHC-P: 1:100-500; IF: 1:100-500; IHC-Fr: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Placenta and lung.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Prostaglandins are produced by the metabolism of arachidonic acid. Prostaglandin E2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues is mediated through binding to the Prostaglandin E2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. Prostaglandin E2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo Prostaglandin E2 induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.
抗原信息
免疫原
A synthesized peptide: human PTGER2
抗原种属
Human
基因名称
PTGER2
基因ID
5732
蛋白名称
Prostaglandin E2 receptor EP2 subtype
Uniprot ID
P43116
功能
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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