Name: Racotumomab
Brand: TargetMol
SKU: T77443
Price: 1650 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,650

现货

2 mg

¥ 2,690

现货

5 mg

¥ 4,970

现货

10 mg

¥ 6,880

现货

25 mg

¥ 9,870

现货

50 mg

¥ 13,700

现货

100 mg

¥ 18,500

现货

生物活性

产品描述	Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody. It can specifically induce an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), which is overexpressed in a variety of solid tumors. Racotumomab reacts with gangliosides containing NU-Glycolyl (NeuGc), thioglycosides, and other antigens expressed in tumors. Racotumomab has anti-cancer activity and can be used in the study of lung cancer.
体外活性	通过诱导针对肿瘤细胞中存在的NeuGcGM3神经节苷脂的特异性体液和细胞免疫应答，racotumomab刺激细胞死亡[4]。
体内活性	在F3II细胞(s.c.)乳腺癌小鼠模型中，racotumomab（50 μg/剂量，i.p.）联合Keyhole limpet hemocyanin (KLH)能够抑制肿瘤生长[2]。针对3LL细胞(s.c.)小鼠皮下移植模型中的肺结节，racotumomab（50 μg/剂量，s.c.）与Pemetrexed（100 mg/kg）联用表现出高效的抑制效果[3]。然而，在3LL细胞(s.c.)小鼠皮下移植模型中，racotumomab（50-200 μg/剂量，s.c.）未展现出显著的抗肿瘤效果[3]。
别名	雷妥莫单抗
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
内毒素	< 1 EU/mg as determined by the LAL method

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	146.6 kDa
CAS No.	946832-34-4

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

储存&溶解度

存储	store at low temperature \| -20°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

Racotumomab