Anti-CPEB1 Antibody (5U97) is a Rabbit antibody targeting CPEB1. Anti-CPEB1 Antibody (5U97) can be used in WB,IP,FCM.

IgG

5U97

Human

WB: 1:1000-2000; IP: 1:20-50; FCM: 1:50-100

Monoclonal

A synthesized peptide: human CPEB1

Human

CPEB1

Cytoplasmic polyadenylation element-binding protein 1

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.