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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CREB Antibody (1B178)

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货号 TMAB-04647

Anti-CREB Antibody (1B178) 是一种 Rabbit 抗体，靶向 CREB。Anti-CREB Antibody (1B178) 可用于 WB,IHC-P,IF,IHC-Fr。

Anti-CREB Antibody (1B178)

Anti-CREB Antibody (1B178)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04647

Anti-CREB Antibody (1B178) 是一种 Rabbit 抗体，靶向 CREB。Anti-CREB Antibody (1B178) 可用于 WB,IHC-P,IF,IHC-Fr。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-CREB Antibody (1B178) is a Rabbit antibody targeting CREB. Anti-CREB Antibody (1B178) can be used in WB,IHC-P,IF,IHC-Fr.
Ig Type
IgG
克隆号
1B178
反应种属
Human,Mouse (predicted:Rat)
应用WBIHC-PIFIHC-Fr
推荐剂量
WB: 1:500-1000; IHC-P: 1:50-200; IF: 1:50-200; IHC-Fr: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液pH7.4, 150mM NaCl, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CREB
抗原种属
Human
基因名称
CREB1
基因ID
1385
蛋白名称
Cyclic AMP-responsive element-binding protein 1
Uniprot ID
P16220
功能
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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