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Anti-MCM5 Antibody (9C193)

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Anti-MCM5 Antibody (9C193)
产品编号 TMAC-02500
别名 P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46

Anti-MCM5 Antibody (9C193) 是一种 Rabbit 抗体，靶向 MCM5。Anti-MCM5 Antibody (9C193) 可用于 WB,IHC。

Anti-MCM5 Antibody (9C193)

Anti-MCM5 Antibody (9C193)

Rating icon 还可以
Anti-MCM5 Antibody (9C193)
产品编号 TMAC-02500 别名 P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46

Anti-MCM5 Antibody (9C193) 是一种 Rabbit 抗体，靶向 MCM5。Anti-MCM5 Antibody (9C193) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-MCM5 Antibody (9C193) is a Rabbit antibody targeting MCM5. Anti-MCM5 Antibody (9C193) can be used in WB,IHC.
别名P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of MCM5 on different lysates using anti-MCM5 antibody at 1/500 dilution. Positive control: Lane 1: Mouse thymus tissue, Lane 2: SiHa.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MCM5 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-MCM5 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-MCM5 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation during apoptosis of the MCM complex, which is composed of, at least, MCM2?C6.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: within C terminal human MCM5
抗原种属
human
Uniprot ID
P33992
化学信息
分子量Theoretical: 82 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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