生物活性

产品描述	IL-13 Protein, Canine, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9N0W9.
生物活性	Immobilized Canine IL-13, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 5.3 ng/ml determined by ELISA (QC Test).
研究背景	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
种属	Canine
表达系统	HEK293 Cells
标签	C-hFc (IgG1)
蛋白编号	Q9N0W9
蛋白构建	Ser19-Arg131
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	38.38 kDa (Predicted); 55-65 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

IL-13 Protein, Canine, Recombinant (hFc)

IL-13 Protein, Canine, Recombinant (hFc)

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