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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-STAT2 Antibody (4N455)

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货号 TMAB-13197

Anti-STAT2 Antibody (4N455) 是一种 Rabbit 抗体，靶向 STAT2。Anti-STAT2 Antibody (4N455) 可用于 WB,ICC/IF。

Anti-STAT2 Antibody (4N455)

Anti-STAT2 Antibody (4N455)

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Rating icon 还可以
货号 TMAB-13197

Anti-STAT2 Antibody (4N455) 是一种 Rabbit 抗体，靶向 STAT2。Anti-STAT2 Antibody (4N455) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-STAT2 Antibody (4N455) is a Rabbit antibody targeting STAT2. Anti-STAT2 Antibody (4N455) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
4N455
反应种属
Human,Mouse
应用WBICC/IF
推荐剂量
WB: 1:500-1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Translocated into the nucleus upon activation by IFN-alpha/beta.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
抗原信息
免疫原
A synthesized peptide: human STAT2
抗原种属
Human
基因名称
STAT2
基因ID
6773
蛋白名称
Signal transducer and activator of transcription 2
Uniprot ID
P52630
功能
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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