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Anti-COPE Antibody (1J185)

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货号 TMAB-04570

Anti-COPE Antibody (1J185) 是一种 Mouse 抗体,靶向 COPE。Anti-COPE Antibody (1J185) 可用于 WB,ICC/IF。

Anti-COPE Antibody (1J185)

Anti-COPE Antibody (1J185)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04570

Anti-COPE Antibody (1J185) 是一种 Mouse 抗体,靶向 COPE。Anti-COPE Antibody (1J185) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 785
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50 μL
¥ 1,395
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100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-COPE Antibody (1J185) is a Mouse antibody targeting COPE. Anti-COPE Antibody (1J185) can be used in WB,ICC/IF.
Ig Type
IgG1, Kappa
克隆号
1J185
反应种属
Human
应用WBICC/IF
推荐剂量
WB: 1:2000-5000; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
抗原信息
基因名称
COPE
基因ID
蛋白名称
Coatomer subunit epsilon
功能
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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