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Anti-PIAS1/2 Antibody (9N378)

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货号 TMAB-11433

Anti-PIAS1/2 Antibody (9N378) 是一种 Rabbit 抗体,靶向 PIAS1/2。Anti-PIAS1/2 Antibody (9N378) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

Anti-PIAS1/2 Antibody (9N378)

Anti-PIAS1/2 Antibody (9N378)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11433

Anti-PIAS1/2 Antibody (9N378) 是一种 Rabbit 抗体,靶向 PIAS1/2。Anti-PIAS1/2 Antibody (9N378) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-PIAS1/2 Antibody (9N378) is a Rabbit antibody targeting PIAS1/2. Anti-PIAS1/2 Antibody (9N378) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
克隆号
9N378
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFIPFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle. Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton.
组织特异性Expressed in numerous tissues with highest level in testis.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.
抗原信息
免疫原
A synthesized peptide: human PIAS1
抗原种属
Human
基因名称
PIAS1
基因ID
蛋白名称
E3 SUMO-protein ligase PIAS1
Uniprot ID
功能
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling.
化学信息
分子量Theoretical: 72, 68 kDa. Actual: 76 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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