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Anti-TFRC Antibody (2M454) 是一种 Rabbit 抗体,靶向 TFRC。Anti-TFRC Antibody (2M454) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-TFRC Antibody (2M454) 是一种 Rabbit 抗体,靶向 TFRC。Anti-TFRC Antibody (2M454) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-TFRC Antibody (2M454) is a Rabbit antibody targeting TFRC. Anti-TFRC Antibody (2M454) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 2M454 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| 免疫原 | KLH conjugated synthetic peptide: human TFRC |
| 抗原种属 | Human |
| 基因名称 | TFRC |
| 基因ID | |
| 蛋白名称 | Transferrin receptor protein 1 |
| Uniprot ID | |
| 功能 | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site. |
| 分子量 | Theoretical: 85 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |