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Anti-SEMA4D Antibody (8V558) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (8V558) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-SEMA4D Antibody (8V558) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (8V558) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-SEMA4D Antibody (8V558) is a Rabbit antibody targeting SEMA4D. Anti-SEMA4D Antibody (8V558) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 8V558 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrICC/IFIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling.Regulates GABAergic synapse development. |
| 免疫原 | A synthesized peptide: human Semaphorin 4D |
| 抗原种属 | Human |
| 基因名称 | SEMA4D |
| 基因ID | |
| 蛋白名称 | Semaphorin-4D |
| Uniprot ID | |
| 功能 | Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. |
| 分子量 | Theoretical: 96 kDa. Actual: 120, 140 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |