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Anti-SEMA4D Antibody (8V558)

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货号 TMAB-12643

Anti-SEMA4D Antibody (8V558) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (8V558) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-SEMA4D Antibody (8V558)

Anti-SEMA4D Antibody (8V558)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12643

Anti-SEMA4D Antibody (8V558) 是一种 Rabbit 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (8V558) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-SEMA4D Antibody (8V558) is a Rabbit antibody targeting SEMA4D. Anti-SEMA4D Antibody (8V558) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
8V558
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling.Regulates GABAergic synapse development.
抗原信息
免疫原
A synthesized peptide: human Semaphorin 4D
抗原种属
Human
基因名称
SEMA4D
基因ID
蛋白名称
Semaphorin-4D
Uniprot ID
功能
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
化学信息
分子量Theoretical: 96 kDa. Actual: 120, 140 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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