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Anti-LYVE1 Antibody (7P115)

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Anti-LYVE1 Antibody (7P115)
产品编号 TMAB-01092

Anti-LYVE1 Antibody (7P115) 是一种 Rabbit 抗体,靶向 LYVE1。Anti-LYVE1 Antibody (7P115) 可用于 WB,ELISA。

Anti-LYVE1 Antibody (7P115)

Anti-LYVE1 Antibody (7P115)

Rating icon 还可以
Anti-LYVE1 Antibody (7P115)
产品编号 TMAB-01092

Anti-LYVE1 Antibody (7P115) 是一种 Rabbit 抗体,靶向 LYVE1。Anti-LYVE1 Antibody (7P115) 可用于 WB,ELISA。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-LYVE1 Antibody (7P115) is a Rabbit antibody targeting LYVE1. Anti-LYVE1 Antibody (7P115) can be used in WB,ELISA.
Ig Type
IgG
克隆号
7P115
交叉反应
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Mouse Spleen tissue lysates
Lane 2: Mouse Blood cell lysates
Lane 3: Mouse LympHnode tissue lysates
Lane 4: Mouse Large intestine tissue lysates
Lane 5: Rat Thyroid gland tissue lysates
Lane 6: Rat Spleen tissue lysates
Lane 7: Rat LympHnode tissue lysates
Lane 8: Rat Large intestine tissue lysates
Lane 9: Human Huvec cell lysates
Lane 10: Human K562 cell lysates
Primary: Anti-LYVE-1 (TMAB-01092) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 58 kDa
应用
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
抗原信息
免疫原
Recombinant Protein: human LYVE1 protein
抗原种属
Human
基因ID
Uniprot ID
研究领域
Endothelial Cell Markers,Endothelium
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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