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Anti-LYVE1 Antibody (7P115) 是一种 Rabbit 抗体,靶向 LYVE1。Anti-LYVE1 Antibody (7P115) 可用于 WB,ELISA。
Anti-LYVE1 Antibody (7P115) 是一种 Rabbit 抗体,靶向 LYVE1。Anti-LYVE1 Antibody (7P115) 可用于 WB,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μL | ¥ 790 | 5日内发货 | |
50 μL | ¥ 1,385 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-LYVE1 Antibody (7P115) is a Rabbit antibody targeting LYVE1. Anti-LYVE1 Antibody (7P115) can be used in WB,ELISA. |
Ig Type | IgG |
克隆号 | 7P115 |
交叉反应 | Human,Mouse,Rat |
验证活性 | Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Blood cell lysates Lane 3: Mouse LympHnode tissue lysates Lane 4: Mouse Large intestine tissue lysates Lane 5: Rat Thyroid gland tissue lysates Lane 6: Rat Spleen tissue lysates Lane 7: Rat LympHnode tissue lysates Lane 8: Rat Large intestine tissue lysates Lane 9: Human Huvec cell lysates Lane 10: Human K562 cell lysates Primary: Anti-LYVE-1 (TMAB-01092) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 58 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. |
构建方式 | Recombinant Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. |
免疫原 | Recombinant Protein: human LYVE1 protein |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Endothelial Cell Markers,Endothelium |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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