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Anti-Podoplanin Antibody (9F461)

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货号 TMAB-11611

Anti-Podoplanin Antibody (9F461) 是一种 Rabbit 抗体,靶向 Podoplanin。Anti-Podoplanin Antibody (9F461) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Podoplanin Antibody (9F461)

Anti-Podoplanin Antibody (9F461)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11611

Anti-Podoplanin Antibody (9F461) 是一种 Rabbit 抗体,靶向 Podoplanin。Anti-Podoplanin Antibody (9F461) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-Podoplanin Antibody (9F461) is a Rabbit antibody targeting Podoplanin. Anti-Podoplanin Antibody (9F461) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9F461
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, microvillus membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane; Single-pass type I membrane protein. Note=Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.
组织特异性Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human Podoplanin
抗原种属
Human
基因名称
PDPN
基因ID
蛋白名称
Podoplanin
Uniprot ID
功能
May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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