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Anti-PMAIP1 Antibody (1B633)

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货号 TMAB-11573

Anti-PMAIP1 Antibody (1B633) 是一种 Rabbit 抗体,靶向 PMAIP1。Anti-PMAIP1 Antibody (1B633) 可用于 WB。

Anti-PMAIP1 Antibody (1B633)

Anti-PMAIP1 Antibody (1B633)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11573

Anti-PMAIP1 Antibody (1B633) 是一种 Rabbit 抗体,靶向 PMAIP1。Anti-PMAIP1 Antibody (1B633) 可用于 WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.
Ig Type
IgG
克隆号
1B633
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
组织特异性Highly expressed in adult T-cell leukemia cell line.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
抗原信息
免疫原
A synthesized peptide: human PMAIP1
抗原种属
Human
基因名称
PMAIP1
基因ID
蛋白名称
Phorbol-12-myristate-13-acetate-induced protein 1
Uniprot ID
功能
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
化学信息
分子量Theoretical: 6 kDa. Actual: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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