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Anti-PMAIP1 Antibody (1B633) 是一种 Rabbit 抗体,靶向 PMAIP1。Anti-PMAIP1 Antibody (1B633) 可用于 WB。
Anti-PMAIP1 Antibody (1B633) 是一种 Rabbit 抗体,靶向 PMAIP1。Anti-PMAIP1 Antibody (1B633) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 1B633 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion. |
| 组织特异性 | Highly expressed in adult T-cell leukemia cell line. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. |
| 免疫原 | A synthesized peptide: human PMAIP1 |
| 抗原种属 | Human |
| 基因名称 | PMAIP1 |
| 基因ID | |
| 蛋白名称 | Phorbol-12-myristate-13-acetate-induced protein 1 |
| Uniprot ID | |
| 功能 | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| 分子量 | Theoretical: 6 kDa. Actual: 16 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |