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Anti-ZO-1 Antibody (3R289)

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货号 TMAB-14456

Anti-ZO-1 Antibody (3R289) 是一种 Rabbit 抗体，靶向 ZO-1。Anti-ZO-1 Antibody (3R289) 可用于 IHC-P,IHC-Fr,IF,FCM,WB。

Anti-ZO-1 Antibody (3R289)

Anti-ZO-1 Antibody (3R289)

一键复制产品信息
Rating icon 还可以
货号 TMAB-14456

Anti-ZO-1 Antibody (3R289) 是一种 Rabbit 抗体，靶向 ZO-1。Anti-ZO-1 Antibody (3R289) 可用于 IHC-P,IHC-Fr,IF,FCM,WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZO-1 Antibody (3R289) is a Rabbit antibody targeting ZO-1. Anti-ZO-1 Antibody (3R289) can be used in IHC-P,IHC-Fr,IF,FCM,WB.
Ig Type
IgG
克隆号
3R289
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFFCMWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Cell junction. Cell junction, gap junction. Note=Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.
组织特异性The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
抗原信息
免疫原
Recombinant Protein: human ZO-1 protein
抗原种属
Human
基因名称
TJP1
基因ID
7082
蛋白名称
Tight junction protein ZO-1
Uniprot ID
Q07157
功能
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
化学信息
分子量Theoretical: 191 kDa.
颜色Transparent
物理性状Liquid
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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