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别名 RAGE, AGER, advanced glycosylation end product-specific receptor
RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1.


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RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 429 | 6-8日内发货 | |
| 10 μg | ¥ 697 | 6-8日内发货 | |
| 20 μg | ¥ 1,150 | 5日内发货 | |
| 50 μg | ¥ 2,260 | 5日内发货 | |
| 100 μg | ¥ 3,820 | 5日内发货 | |
| 200 μg | ¥ 6,750 | 5日内发货 | |
| 500 μg | ¥ 14,200 | 5日内发货 |
| 产品描述 | RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1. |
| 生物活性 | Human AGER, His Tag immobilized on CM5 Chip can bind Human HMGB1, His Tag with an affinity constant of 0.19 μM as determined in SPR assay (Biacore T200). |
| 研究背景 | The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | Q15109-1 |
| 蛋白构建 | Ala23- Ala344 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | RAGE, AGER, advanced glycosylation end product-specific receptor |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 35.3 kDa (Predicted); 50-60 kDa (Due to glycosylation) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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