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Anti-Collagen IV Antibody (6X572) 是一种 Rabbit 抗体,靶向 Collagen IV。Anti-Collagen IV Antibody (6X572) 可用于 IHC-P,IHC-Fr,IF。
Anti-Collagen IV Antibody (6X572) 是一种 Rabbit 抗体,靶向 Collagen IV。Anti-Collagen IV Antibody (6X572) 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Collagen IV Antibody (6X572) is a Rabbit antibody targeting Collagen IV. Anti-Collagen IV Antibody (6X572) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 6X572 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix, basement membrane. |
| 组织特异性 | Highly expressed in placenta. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | PBS (pH7.2) with 40% Glycerol, 0.05% BSA and 0.02% Proclin300. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human Collagen IV |
| 抗原种属 | Human |
| 基因名称 | COL4A1 |
| 基因ID | |
| 蛋白名称 | Collagen alpha-1(IV) chain |
| Uniprot ID | |
| 功能 | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. |
| 分子量 | Theoretical: 161 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |