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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LGI1 Antibody (6O132)

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货号 TMAB-08289

Anti-LGI1 Antibody (6O132) 是一种 Rabbit 抗体，靶向 LGI1。Anti-LGI1 Antibody (6O132) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

Anti-LGI1 Antibody (6O132)

Anti-LGI1 Antibody (6O132)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08289

Anti-LGI1 Antibody (6O132) 是一种 Rabbit 抗体，靶向 LGI1。Anti-LGI1 Antibody (6O132) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-LGI1 Antibody (6O132) is a Rabbit antibody targeting LGI1. Anti-LGI1 Antibody (6O132) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
克隆号
6O132
反应种属
Human (predicted:Mouse,Rat)
应用WBIHC-PIHC-FrIPIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted. Cell junction, synapse (By similarity). Note=Isoform 1 but not isoform 2 is secreted. Isoform 1 is enriched in the Golgi apparatus while isoform 2 accumulates in the endoplasmic reticulum.
组织特异性Predominantly expressed in neural tissues, especially in brain. Expression is reduced in low-grade brain tumors and significantly reduced or absent in malignant gliomas. Isoform 1 is absent in the cerebellum and is detectable in the occipital cortex and hippocampus; higher amounts are observed in the parietal and frontal cortices, putamen, and, particularly, in the temporal neocortex, where it is 3.5 times more abundant than in the hippocampus (at protein level). Isoform 3 shows the highest expression in the occipital cortex and the lowest in the hippocampus (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity).
抗原信息
免疫原
A synthesized peptide: human Epitempin 1
抗原种属
Human
基因名称
LGI1
基因ID
9211
蛋白名称
Leucine-rich glioma-inactivated protein 1
Uniprot ID
O95970
功能
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
化学信息
分子量Theoretical: 64 kDa. Actual: 64 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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