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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TSC1 Antibody (6O649)

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货号 TMAB-13857

Anti-TSC1 Antibody (6O649) 是一种 Rabbit 抗体，靶向 TSC1。Anti-TSC1 Antibody (6O649) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-TSC1 Antibody (6O649)

Anti-TSC1 Antibody (6O649)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13857

Anti-TSC1 Antibody (6O649) 是一种 Rabbit 抗体，靶向 TSC1。Anti-TSC1 Antibody (6O649) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-TSC1 Antibody (6O649) is a Rabbit antibody targeting TSC1. Anti-TSC1 Antibody (6O649) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
6O649
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes.
组织特异性Highly expressed in skeletal muscle, followed by heart, brain, placenta, pancreas, lung, liver and kidney. Also expressed in embryonic kidney cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth.
抗原信息
免疫原
A synthesized peptide: human Hamartin
抗原种属
Human
基因名称
TSC1
基因ID
7248
蛋白名称
Hamartin
Uniprot ID
Q92574
功能
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
化学信息
分子量Theoretical: 130 kDa. Actual: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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