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Anti-FOLH1 Antibody (3M578)

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货号 TMAB-06104

Anti-FOLH1 Antibody (3M578) 是一种 Rabbit 抗体,靶向 FOLH1。Anti-FOLH1 Antibody (3M578) 可用于 IHC-P,IHC-Fr,IF。

Anti-FOLH1 Antibody (3M578)

Anti-FOLH1 Antibody (3M578)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06104

Anti-FOLH1 Antibody (3M578) 是一种 Rabbit 抗体,靶向 FOLH1。Anti-FOLH1 Antibody (3M578) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-FOLH1 Antibody (3M578) is a Rabbit antibody targeting FOLH1. Anti-FOLH1 Antibody (3M578) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3M578
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm.
组织特异性Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-2 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants. Subunit : Homodimer.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FOLH1
抗原种属
Human
基因名称
FOLH1
基因ID
蛋白名称
Glutamate carboxypeptidase 2
Uniprot ID
化学信息
分子量Theoretical: 84 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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