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Anti-c-Jun Antibody (2U383)

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货号 TMAB-04375

Anti-c-Jun Antibody (2U383) 是一种 Rabbit 抗体,靶向 c-Jun。Anti-c-Jun Antibody (2U383) 可用于 WB。

Anti-c-Jun Antibody (2U383)

Anti-c-Jun Antibody (2U383)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04375

Anti-c-Jun Antibody (2U383) 是一种 Rabbit 抗体,靶向 c-Jun。Anti-c-Jun Antibody (2U383) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-c-Jun Antibody (2U383) is a Rabbit antibody targeting c-Jun. Anti-c-Jun Antibody (2U383) can be used in WB.
Ig Type
IgG
克隆号
2U383
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.
抗原信息
免疫原
A synthesized peptide: human c Jun
抗原种属
Human
基因名称
JUN
基因ID
蛋白名称
Transcription factor AP-1
Uniprot ID
功能
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
化学信息
分子量Theoretical: 43 kDa. Actual: 43/36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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