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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Progesterone Receptor Antibody (8O274)

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货号 TMAB-11773

Anti-Progesterone Receptor Antibody (8O274) 是一种 Rabbit 抗体，靶向 Progesterone Receptor。Anti-Progesterone Receptor Antibody (8O274) 可用于 IHC-P,IHC-Fr,IF,WB。

Anti-Progesterone Receptor Antibody (8O274)

Anti-Progesterone Receptor Antibody (8O274)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11773

Anti-Progesterone Receptor Antibody (8O274) 是一种 Rabbit 抗体，靶向 Progesterone Receptor。Anti-Progesterone Receptor Antibody (8O274) 可用于 IHC-P,IHC-Fr,IF,WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-Progesterone Receptor Antibody (8O274) is a Rabbit antibody targeting Progesterone Receptor. Anti-Progesterone Receptor Antibody (8O274) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG
克隆号
8O274
反应种属
Human
应用IHC-PIHC-FrIFWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases. Isoform A: Nucleus. Cytoplasm. Note=Mainly nuclear.
组织特异性Isoform A: Nucleus. Cytoplasm. Note=Mainly nuclear.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. ER alpha and ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
抗原信息
免疫原
A synthesized peptide: human Progesterone receptor
抗原种属
Human
基因名称
PGR
基因ID
5241
蛋白名称
Progesterone receptor
Uniprot ID
P06401
功能
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.
Isoform A is inactive in stimulating c-Src/MAPK signaling on hormone stimulation.
化学信息
分子量Theoretical: 103 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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