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Anti-SBDS Antibody (8J57)

Name: Anti-SBDS Antibody (8J57)
Brand: TargetMol
SKU: TMAB-12545
Rating: 4.5 (1 reviews)

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货号 TMAB-12545

Anti-SBDS Antibody (8J57) 是一种 Mouse 抗体，靶向 SBDS。Anti-SBDS Antibody (8J57) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-SBDS Antibody (8J57)

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货号 TMAB-12545

Anti-SBDS Antibody (8J57) 是一种 Mouse 抗体，靶向 SBDS。Anti-SBDS Antibody (8J57) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

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生物活性

产品描述	Anti-SBDS Antibody (8J57) is a Mouse antibody targeting SBDS. Anti-SBDS Antibody (8J57) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type	IgG2a, Kappa
克隆号	8J57
反应种属	Human,Mouse,Rat
应用	WB IHC-P IHC-Fr ICC/IF IF
推荐剂量	WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类	Monoclonal
宿主来源	Mouse
亚细胞定位	Cytoplasm. Nucleus > nucleolus. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 and PubMed:17475909). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase.
组织特异性	Widely expressed.
构建方式	Recombinant Antibody
纯化方式	Protein G purified
性状	Liquid
缓冲液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度	1mg/ml
研究背景	This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jul 2008]

抗原信息

基因名称	SBDS
基因ID	51119
蛋白名称	Ribosome maturation protein SBDS
功能	Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

储存&溶解度

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式	Shipping with blue ice.
存储	store at low temperature \| -20°C for 1 year

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