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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ZEB1 Antibody (2Q357)

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货号 TMAB-14285

Anti-ZEB1 Antibody (2Q357) 是一种 Rabbit 抗体，靶向 ZEB1。Anti-ZEB1 Antibody (2Q357) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-ZEB1 Antibody (2Q357)

Anti-ZEB1 Antibody (2Q357)

一键复制产品信息
Rating icon 还可以
货号 TMAB-14285

Anti-ZEB1 Antibody (2Q357) 是一种 Rabbit 抗体，靶向 ZEB1。Anti-ZEB1 Antibody (2Q357) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZEB1 Antibody (2Q357) is a Rabbit antibody targeting ZEB1. Anti-ZEB1 Antibody (2Q357) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
2Q357
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Colocalizes with SMARCA4/BRG1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). Expressed in heart and skeletal muscle, but not in liver, spleen, or pancreas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Inhibits interleukin-2 (IL-2) gene expression. May be responsible for transcriptional repression of the IL-2 gene. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type.
抗原信息
免疫原
A synthesized peptide: human ZEB1
抗原种属
Human
基因名称
ZEB1
基因ID
6935
蛋白名称
Zinc finger E-box-binding homeobox 1
Uniprot ID
P37275
功能
Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
化学信息
分子量Theoretical: 124 kDa. Actual: 200 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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