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Anti-SUV39H2 Antibody (8R663)
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产品编号 TMAC-03923
别名 SUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Su(var)3-9 homolog 2, Su(var)3 9 homolog 2, Su(var)3 9 Drosophila homolog of 2, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Lysine N-methyltransferase 1B, Lysine N methyltransferase 1B, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone lysine N methyltransferase SUV39H2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone H3-K9 methyltransferase 2, Histone H3 K9 methyltransferase 2, H3-K9-HMTase 2, H3 K9 HMTase 2, FLJ23414
Anti-SUV39H2 Antibody (8R663) 是一种 Rabbit 抗体，靶向 SUV39H2。Anti-SUV39H2 Antibody (8R663) 可用于 WB,IHC,IP。
Anti-SUV39H2 Antibody (8R663)
Anti-SUV39H2 Antibody (8R663)
还可以产品编号 TMAC-03923 别名 SUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Su(var)3-9 homolog 2, Su(var)3 9 homolog 2, Su(var)3 9 Drosophila homolog of 2, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Lysine N-methyltransferase 1B, Lysine N methyltransferase 1B, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone lysine N methyltransferase SUV39H2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone H3-K9 methyltransferase 2, Histone H3 K9 methyltransferase 2, H3-K9-HMTase 2, H3 K9 HMTase 2, FLJ23414
Anti-SUV39H2 Antibody (8R663) 是一种 Rabbit 抗体，靶向 SUV39H2。Anti-SUV39H2 Antibody (8R663) 可用于 WB,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP. |
| 别名 | SUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Su(var)3-9 homolog 2, Su(var)3 9 homolog 2, Su(var)3 9 Drosophila homolog of 2, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Lysine N-methyltransferase 1B, Lysine N methyltransferase 1B, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone lysine N methyltransferase SUV39H2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone H3-K9 methyltransferase 2, Histone H3 K9 methyltransferase 2, H3-K9-HMTase 2, H3 K9 HMTase 2, FLJ23414 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of SUV39H2 on SiHa cell (1) and A549 cell (2) lysate using anti- SUV39H2 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti- SUV39H2 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation. |
| 偶联 | Unconjugated |
| 免疫原 | A synthesized peptide: within Human SUV39H2 aa 350 to the C-terminus |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 40/47 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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