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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TERF1 Antibody (3H363)

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货号 TMAB-13454

Anti-TERF1 Antibody (3H363) 是一种 Rabbit 抗体，靶向 TERF1。Anti-TERF1 Antibody (3H363) 可用于 WB,ICC/IF。

Anti-TERF1 Antibody (3H363)

Anti-TERF1 Antibody (3H363)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13454

Anti-TERF1 Antibody (3H363) 是一种 Rabbit 抗体，靶向 TERF1。Anti-TERF1 Antibody (3H363) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-TERF1 Antibody (3H363) is a Rabbit antibody targeting TERF1. Anti-TERF1 Antibody (3H363) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
3H363
反应种属
Human (predicted:Mouse)
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm; cytoskeleton; spindle. Chromosome; telomere. Colocalizes with telomeric DNA in interphase and metaphase cells and is located at chromosome ends during metaphase. Associates with the mitotic spindle.
组织特异性Highly expressed and ubiquitous. Isoform Pin2 predominates.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression.
抗原信息
免疫原
A synthesized peptide: human TERF1
抗原种属
Human
基因名称
TERF1
基因ID
7013
蛋白名称
Telomeric repeat-binding factor 1
Uniprot ID
P54274
功能
Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
化学信息
分子量Theoretical: 50 kDa. Actual: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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