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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ALOX15 Antibody (8G848)

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货号 TMAB-02448

Anti-ALOX15 Antibody (8G848) 是一种 Rabbit 抗体，靶向 ALOX15。Anti-ALOX15 Antibody (8G848) 可用于 IHC-P,IHC-Fr,IF。

Anti-ALOX15 Antibody (8G848)

Anti-ALOX15 Antibody (8G848)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02448

Anti-ALOX15 Antibody (8G848) 是一种 Rabbit 抗体，靶向 ALOX15。Anti-ALOX15 Antibody (8G848) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ALOX15 Antibody (8G848) is a Rabbit antibody targeting ALOX15. Anti-ALOX15 Antibody (8G848) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
8G848
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Skeletal muscle and brain (cerebellum and hippocampus).
构建方式Recombinant Antibody
纯化方式Protein A purified
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ALOX15
抗原种属
Human
基因名称
ALOX15
基因ID
246
蛋白名称
Polyunsaturated fatty acid lipoxygenase ALOX15
Uniprot ID
P16050
功能
Oxygenase and 14,15-leukotriene A4 synthase activity. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid.
化学信息
分子量Theoretical: 73 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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