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Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His)

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产品编号 TMPY-01873U

Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P02786.

Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His)

一键复制产品信息

产品编号 TMPY-01873U

Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P02786.

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生物活性	Immobilized Human Transferrin R, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human Transferrin, His Avi Tag with the EC50 of 14.3 ng/ml determined by ELISA. (QC Test) Immobilized Human Transferrin R, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Transferrin R Antibody, hFc Tag with the EC50 of 6.8 ng/ml determined by ELISA. Loaded Anti-Transferrin R Antibody, hFc Tag on ProA-Biosensor can bind Human Transferrin R, His Tag with an affinity constant of 0.65 nM as determined in BLI assay (Gator® Prime).
产品描述	Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P02786.
种属	Human
表达系统	HEK293 Cells
标签	N-His
蛋白编号	P02786
别名	TRFR,transferrin receptor,TR,TFR1,TFR,T9,p90,CD71
蛋白构建	Cys89-Phe760
蛋白纯度	> 90% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
分子量	77.25 kDa (Predicted); 78-90 kDa (Due to glycosylation); 125-180 kDa (SEC-MALS)
内毒素	< 0.1 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.