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Anti-LAMP1 Antibody (2T47)

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货号 TMAB-08210

Anti-LAMP1 Antibody (2T47) 是一种抗体,靶向 LAMP1。Anti-LAMP1 Antibody (2T47) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-LAMP1 Antibody (2T47)

Anti-LAMP1 Antibody (2T47)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08210

Anti-LAMP1 Antibody (2T47) 是一种抗体,靶向 LAMP1。Anti-LAMP1 Antibody (2T47) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-LAMP1 Antibody (2T47) is a antibody targeting LAMP1. Anti-LAMP1 Antibody (2T47) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2T47
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-5000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
抗原信息
免疫原
Recombinant Protein: human LAMP1 protein
抗原种属
Human
基因名称
LAMP1
基因ID
蛋白名称
Lysosome-associated membrane glycoprotein 1
Uniprot ID
功能
Presents carbohydrate ligands to selectins. Also mplicated in tumor cell metastasis.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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