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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SKP1 Antibody (1B386)

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货号 TMAB-12828

Anti-SKP1 Antibody (1B386) 是一种 Rabbit 抗体，靶向 SKP1。Anti-SKP1 Antibody (1B386) 可用于 WB,ICC/IF,FCM。

Anti-SKP1 Antibody (1B386)

Anti-SKP1 Antibody (1B386)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12828

Anti-SKP1 Antibody (1B386) 是一种 Rabbit 抗体，靶向 SKP1。Anti-SKP1 Antibody (1B386) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-SKP1 Antibody (1B386) is a Rabbit antibody targeting SKP1. Anti-SKP1 Antibody (1B386) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
1B386
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.
抗原信息
免疫原
A synthesized peptide: human SKP1
抗原种属
Human
基因名称
SKP1
基因ID
6500
蛋白名称
S-phase kinase-associated protein 1
Uniprot ID
P63208
功能
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
化学信息
分子量Theoretical: 19 kDa. Actual: 19 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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