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GDF-15 Protein, Human, Recombinant (hFc) V2

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产品编号 TMPY-01073U

GDF-15 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q99988.

GDF-15 Protein, Human, Recombinant (hFc) V2

一键复制产品信息

产品编号 TMPY-01073U

GDF-15 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q99988.

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产品信息

生物活性	Immobilized Human GFRAL, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GDF15, hFc Tag with the EC50 of 2.5 ng/ml determined by ELISA.
产品描述	GDF-15 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q99988.
种属	Human
表达系统	HEK293 Cells
蛋白编号	Q99988
别名	PTGFB,PLAB,PDF,NAG-1,MIC-1,MIC1,growth differentiation factor 15,GDF-15
蛋白构建	Ala197-Ile308
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 92% as determined by HPLC
分子量	37.9 kDa (Predicted); 40-50 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.