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Anti-FGF2 Antibody (7I158)

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货号 TMAB-05987

Anti-FGF2 Antibody (7I158) 是一种 Rabbit 抗体，靶向 FGF2。Anti-FGF2 Antibody (7I158) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-FGF2 Antibody (7I158)

Anti-FGF2 Antibody (7I158)

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Rating icon 还可以
货号 TMAB-05987

Anti-FGF2 Antibody (7I158) 是一种 Rabbit 抗体，靶向 FGF2。Anti-FGF2 Antibody (7I158) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-FGF2 Antibody (7I158) is a Rabbit antibody targeting FGF2. Anti-FGF2 Antibody (7I158) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
7I158
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.
组织特异性Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
A synthesized peptide: human FGF2
抗原种属
Human
基因名称
FGF2
基因ID
2247
蛋白名称
Fibroblast growth factor 2
Uniprot ID
P09038
功能
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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