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Anti-QKI Antibody (4N982) 是一种 Rabbit 抗体,靶向 QKI。Anti-QKI Antibody (4N982) 可用于 WB,ICC/IF,IP。
Anti-QKI Antibody (4N982) 是一种 Rabbit 抗体,靶向 QKI。Anti-QKI Antibody (4N982) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-QKI Antibody (4N982) is a Rabbit antibody targeting QKI. Anti-QKI Antibody (4N982) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| 克隆号 | 4N982 |
| 反应种属 | Human,Mouse |
| 应用 | WBICC/IFIP |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. |
| 组织特异性 | Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | RNA reader protein, which recognizes and binds specific RNAs, thereby regulating RNA metabolic processes, such as pre-mRNA splicing, circular RNA (circRNA) formation, mRNA export, mRNA stability and/or translation.Involved in various cellular processes, such as mRNA storage into stress granules, apoptosis, lipid deposition, interferon response, glial cell fate and development. |
| 免疫原 | A synthesized peptide: human QKI |
| 抗原种属 | Human |
| 基因名称 | QKI |
| 基因ID | |
| 蛋白名称 | Protein quaking |
| Uniprot ID | |
| 功能 | RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor. |
| 分子量 | Theoretical: 38 kDa. Actual: 38 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |