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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RPE65 Antibody (7P282)

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货号 TMAB-12352

Anti-RPE65 Antibody (7P282) 是一种 Rabbit 抗体，靶向 RPE65。Anti-RPE65 Antibody (7P282) 可用于 WB,IP,IHC-P,IHC-Fr,IF。

Anti-RPE65 Antibody (7P282)

Anti-RPE65 Antibody (7P282)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12352

Anti-RPE65 Antibody (7P282) 是一种 Rabbit 抗体，靶向 RPE65。Anti-RPE65 Antibody (7P282) 可用于 WB,IP,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-RPE65 Antibody (7P282) is a Rabbit antibody targeting RPE65. Anti-RPE65 Antibody (7P282) can be used in WB,IP,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
7P282
反应种属
Mouse,Rat (predicted:Human)
应用WBIPIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IP: 1:20-50; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
组织特异性Retinal pigment epithelium specific.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore
抗原信息
免疫原
A synthesized peptide: human RPE65
抗原种属
Human
基因名称
RPE65
基因ID
6121
蛋白名称
Retinoid isomerohydrolase
Uniprot ID
Q16518
功能
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
化学信息
分子量Theoretical: 61 kDa. Actual: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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