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Anti-UBE2I Antibody (3Q966)

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货号 TMAB-13935

Anti-UBE2I Antibody (3Q966) 是一种 Rabbit 抗体,靶向 UBE2I。Anti-UBE2I Antibody (3Q966) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

Anti-UBE2I Antibody (3Q966)

Anti-UBE2I Antibody (3Q966)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13935

Anti-UBE2I Antibody (3Q966) 是一种 Rabbit 抗体,靶向 UBE2I。Anti-UBE2I Antibody (3Q966) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-UBE2I Antibody (3Q966) is a Rabbit antibody targeting UBE2I. Anti-UBE2I Antibody (3Q966) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
克隆号
3Q966
反应种属
Human,Mouse (predicted:Rat)
应用WBIHC-PIHC-FrICC/IFIFIPFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.
组织特异性Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.
抗原信息
免疫原
A synthesized peptide: human UBE2I
抗原种属
Human
基因名称
UBE2I
基因ID
蛋白名称
SUMO-conjugating enzyme UBC9
Uniprot ID
功能
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation.
化学信息
分子量Theoretical: 18 kDa. Actual: 18 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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