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Anti-ULBP1 Antibody (9B852)

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货号 TMAB-13987

Anti-ULBP1 Antibody (9B852) 是一种 Rabbit 抗体，靶向 ULBP1。Anti-ULBP1 Antibody (9B852) 可用于 WB。

Anti-ULBP1 Antibody (9B852)

Anti-ULBP1 Antibody (9B852)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13987

Anti-ULBP1 Antibody (9B852) 是一种 Rabbit 抗体，靶向 ULBP1。Anti-ULBP1 Antibody (9B852) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ULBP1 Antibody (9B852) is a Rabbit antibody targeting ULBP1. Anti-ULBP1 Antibody (9B852) can be used in WB.
Ig Type
IgG
克隆号
9B852
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. Note=Detected intracellularly in the endoplasmic reticulum of CMV-infected fibroblasts.
组织特异性Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
抗原信息
免疫原
A synthesized peptide: human ULBP1
抗原种属
Human
基因名称
ULBP1
基因ID
80329
蛋白名称
UL16-binding protein 1
Uniprot ID
Q9BZM6
功能
Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
化学信息
分子量Theoretical: 28 kDa. Actual: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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