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Anti-Cyclin E1 Antibody (1V718) 是一种 Rabbit 抗体,靶向 Cyclin E1。Anti-Cyclin E1 Antibody (1V718) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-Cyclin E1 Antibody (1V718) 是一种 Rabbit 抗体,靶向 Cyclin E1。Anti-Cyclin E1 Antibody (1V718) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-Cyclin E1 Antibody (1V718) is a Rabbit antibody targeting Cyclin E1. Anti-Cyclin E1 Antibody (1V718) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 1V718 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrICC/IFIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
| 免疫原 | A synthesized peptide: human Cyclin E1 |
| 抗原种属 | Human |
| 基因名称 | CCNE1 |
| 基因ID | |
| 蛋白名称 | G1/S-specific cyclin-E1 |
| Uniprot ID | |
| 功能 | Essential for the control of the cell cycle at the G1/S (start) transition. |
| 分子量 | Theoretical: 45 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |