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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ESE1 Antibody (2C543)

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货号 TMAB-05696

Anti-ESE1 Antibody (2C543) 是一种 Rabbit 抗体，靶向 ESE1。Anti-ESE1 Antibody (2C543) 可用于 WB,FCM,ICC/IF。

Anti-ESE1 Antibody (2C543)

Anti-ESE1 Antibody (2C543)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05696

Anti-ESE1 Antibody (2C543) 是一种 Rabbit 抗体，靶向 ESE1。Anti-ESE1 Antibody (2C543) 可用于 WB,FCM,ICC/IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ESE1 Antibody (2C543) is a Rabbit antibody targeting ESE1. Anti-ESE1 Antibody (2C543) can be used in WB,FCM,ICC/IF.
Ig Type
IgG
克隆号
2C543
反应种属
Human,Mouse,Rat
应用WBFCMICC/IF
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Localizes to the cytoplasm where it has been shown to transform MCF-12A mammary epithelial cells via a novel cytoplasmic mechanism. Also transiently expressed and localized to the nucleus where it induces apoptosis in non-transformed breast epithelial cells MCF-10A and MCF-12A via a transcription-dependent mechanism.
组织特异性Expressed exclusively in tissues containing a high content of terminally differentiated epithelial cells including mammary gland, colon, trachea, kidney, prostate, uterus, stomach and skin.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter.
抗原信息
免疫原
A synthesized peptide: human ELF3
抗原种属
Human
基因名称
ELF3
基因ID
1999
蛋白名称
ETS-related transcription factor Elf-3
Uniprot ID
P78545
功能
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
化学信息
分子量Theoretical: 41 kDa. Actual: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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