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别名 伊玛鲁单抗, BAX69, BAX 69, Anti-Human MIF Recombinant Antibody
Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.

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Imalumab (BAX69) is a recombinant humanised monoclonal antibody that targets and inhibits MIF (macrophage inhibitory factor), exhibiting anticancer activity. It is applicable for advanced solid tumours such as ovarian cancer and non-small cell lung cancer.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 2,820 | 现货 | |
| 5 mg | ¥ 6,430 | 现货 | |
| 10 mg | ¥ 8,670 | 现货 | |
| 25 mg | ¥ 12,800 | 现货 | |
| 50 mg | ¥ 17,300 | 现货 |
| 产品描述 | Imalumab(BAX69)是一种重组的人源化单克隆抗体,靶向并抑制MIF(巨噬细胞抑制因子),具有抗癌活性,可用于晚期实体瘤,如卵巢癌和非小细胞肺癌。 |
| 体外活性 | Imalumab 能够特异性地与氧化型巨噬细胞移动抑制因子(oxMIF)结合,从而干扰其下游信号通路。Imalumab可诱导抗体依赖性细胞毒性(ADCC)和抗体依赖性细胞吞噬作用(ADCP),并能在人外周血单个核细胞(PBMC)中诱导细胞裂解,EC50 为 0.7-39.2 nM[[2]。 |
| 体内活性 | 在 BALB/c 小鼠模型中,Imalumab (5 mg/kg, 静脉注射) 的终末半衰期为 37.4 小时[2]。 |
| 别名 | 伊玛鲁单抗, BAX69, BAX 69, Anti-Human MIF Recombinant Antibody |
| 反应种属 | Human |
| 应用 | ELISA FCM Functional assay |
| 抗体种类 | Monoclonal |
| 内毒素 | <1.0 EU/mg |
| 偶联 | Unconjugated |
| 基因ID | |
| Uniprot ID | |
| 靶点 | MIF |
| CAS No. | 1430205-07-4 |
| 颜色 | Transparent |
| 物理性状 | Liquid |
| 同型 | Human IgG1 kappa |
| 推荐同型对照 |
| 存储 | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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