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顶部生物活性储存和溶解信息计算器

Anti-Phospho-CDC6 (Ser54) Antibody (7Q442)

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Anti-Phospho-CDC6 (Ser54) Antibody (7Q442)
产品编号 TMAC-03196
别名 p-CDC6 (Ser54), p-CDC6 (S54), CDC6 (p-Ser54), CDC6 (p-S54)

Anti-Phospho-CDC6 (S54) Antibody (7Q442) 是一种 Rabbit 抗体，靶向 Phospho-CDC6 (S54)。Anti-Phospho-CDC6 (S54) Antibody (7Q442) 可用于 WB,ICC/IF。

Anti-Phospho-CDC6 (Ser54) Antibody (7Q442)

Anti-Phospho-CDC6 (Ser54) Antibody (7Q442)

Rating icon 还可以
Anti-Phospho-CDC6 (Ser54) Antibody (7Q442)
产品编号 TMAC-03196 别名 p-CDC6 (Ser54), p-CDC6 (S54), CDC6 (p-Ser54), CDC6 (p-S54)

Anti-Phospho-CDC6 (S54) Antibody (7Q442) 是一种 Rabbit 抗体，靶向 Phospho-CDC6 (S54)。Anti-Phospho-CDC6 (S54) Antibody (7Q442) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,495
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100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CDC6 (Ser54) Antibody (7Q442) 是一种 Rabbit 抗体，靶向 Phospho-CDC6 (Ser54)。Anti-Phospho-CDC6 (Ser54) Antibody (7Q442) 可用于 WB,ICC/IF。
别名p-CDC6 (Ser54), p-CDC6 (S54), CDC6 (p-Ser54), CDC6 (p-S54)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Phospho-Cdc6 (S54) on Jurkat cells lysates using anti-Phospho-Cdc6 (S54) antibody at 1/1,000 dilution.
2. ICC staining Phospho-Cdc6 (S54) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Phospho-Cdc6 (S54) in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Phospho-Cdc6 (S54) in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein Tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory Tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (x complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human Cdc6 around the phosphorylation site of Ser54
抗原种属
human
Uniprot ID
Q99741
化学信息
分子量Theoretical: 63 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pCDC6 (Ser54)pCDC6 (S54)CDC6 (pSer54)CDC6 (pS54)CDC6 (phospho-Ser54)CDC6 (phospho-S54)

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4个月前
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