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Anti-PLAUR Antibody (5S385) 是一种 Rabbit 抗体,靶向 PLAUR。Anti-PLAUR Antibody (5S385) 可用于 WB。
Anti-PLAUR Antibody (5S385) 是一种 Rabbit 抗体,靶向 PLAUR。Anti-PLAUR Antibody (5S385) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-PLAUR Antibody (5S385) is a Rabbit antibody targeting PLAUR. Anti-PLAUR Antibody (5S385) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 5S385 |
| 反应种属 | Human |
| 验证活性 | U-937 (H) cells were treated with or without PMA (200 nM) for 72 h, 25 μg total protein per lane of cell lysates (see on figure) probed with PLAUR monoclonal antibody, unconjugated (TMAB-11528) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| 应用 | WB |
| 推荐剂量 | WB=1:1000-5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Secreted (Probable). |
| 组织特异性 | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq]. |
| 免疫原 | Recombinant Protein: human PLAUR protein |
| 抗原种属 | Human |
| 基因名称 | PLAUR |
| 基因ID | |
| 蛋白名称 | Urokinase plasminogen activator surface receptor |
| Uniprot ID | |
| 功能 | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |