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Anti-PLAUR Antibody (5S385)

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货号 TMAB-11528

Anti-PLAUR Antibody (5S385) 是一种 Rabbit 抗体,靶向 PLAUR。Anti-PLAUR Antibody (5S385) 可用于 WB。

Anti-PLAUR Antibody (5S385)

Anti-PLAUR Antibody (5S385)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11528

Anti-PLAUR Antibody (5S385) 是一种 Rabbit 抗体,靶向 PLAUR。Anti-PLAUR Antibody (5S385) 可用于 WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-PLAUR Antibody (5S385) is a Rabbit antibody targeting PLAUR. Anti-PLAUR Antibody (5S385) can be used in WB.
Ig Type
IgG
克隆号
5S385
反应种属
Human
验证活性
U-937 (H) cells were treated with or without PMA (200 nM) for 72 h, 25 μg total protein per lane of cell lysates (see on figure) probed with PLAUR monoclonal antibody, unconjugated (TMAB-11528) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB=1:1000-5000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Secreted (Probable).
组织特异性Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq].
抗原信息
免疫原
Recombinant Protein: human PLAUR protein
抗原种属
Human
基因名称
PLAUR
基因ID
蛋白名称
Urokinase plasminogen activator surface receptor
Uniprot ID
功能
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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