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Anti-TFE3 Antibody (5K387) 是一种 Rabbit 抗体,靶向 TFE3。Anti-TFE3 Antibody (5K387) 可用于 IHC-P,IHC-Fr,IF。
Anti-TFE3 Antibody (5K387) 是一种 Rabbit 抗体,靶向 TFE3。Anti-TFE3 Antibody (5K387) 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 5K387 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitous in fetal and adult tissues. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response . Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. |
| 免疫原 | A synthesized peptide: human TFE3 |
| 抗原种属 | Human |
| 基因名称 | TFE3 |
| 基因ID | |
| 蛋白名称 | Transcription factor E3 |
| Uniprot ID | |
| 功能 | Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
| 分子量 | Theoretical: 62 kDa. Actual: 62 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |