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Anti-TFE3 Antibody (5K387)

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货号 TMAB-13469

Anti-TFE3 Antibody (5K387) 是一种 Rabbit 抗体,靶向 TFE3。Anti-TFE3 Antibody (5K387) 可用于 IHC-P,IHC-Fr,IF。

Anti-TFE3 Antibody (5K387)

Anti-TFE3 Antibody (5K387)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13469

Anti-TFE3 Antibody (5K387) 是一种 Rabbit 抗体,靶向 TFE3。Anti-TFE3 Antibody (5K387) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
5K387
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitous in fetal and adult tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response . Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF.
抗原信息
免疫原
A synthesized peptide: human TFE3
抗原种属
Human
基因名称
TFE3
基因ID
蛋白名称
Transcription factor E3
Uniprot ID
功能
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
化学信息
分子量Theoretical: 62 kDa. Actual: 62 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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