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Anti-Fbx32 Antibody (4A434)

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Anti-Fbx32 Antibody (4A434)
产品编号 TMAB-00661

Anti-Fbx32 Antibody (4A434) 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Antibody (4A434) 可用于 WB,ICC/IF。

Anti-Fbx32 Antibody (4A434)

Anti-Fbx32 Antibody (4A434)

Rating icon 还可以
Anti-Fbx32 Antibody (4A434)
产品编号 TMAB-00661

Anti-Fbx32 Antibody (4A434) 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Antibody (4A434) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Fbx32 Antibody (4A434) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (4A434) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
4A434
交叉反应
Mouse,Rat (predicted:Human)
验证活性
25 μg total protein per Lane of various lysates probed with Fbx32 monoclonal antibody, unconjugated (TMAB-00661) at 1:10000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
应用
WB
ICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between Cytoplasm and the nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Fbx32 is an E3 ubiquitin ligase that initiates ATP dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. It is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. It is also thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. Fbx32 interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD.
抗原信息
免疫原
A synthesized peptide: human FBXO32
抗原种属
Human
基因ID
114907
Uniprot ID
Q969P5
研究领域
Hypertrophy,F Box E3 Ligase,SCF Complex E3 Ligase,Myogenesis
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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