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Anti-CYP1A2 Antibody (9D8)

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货号 TMAB-04871

Anti-CYP1A2 Antibody (9D8) 是一种 Rabbit 抗体,靶向 CYP1A2。Anti-CYP1A2 Antibody (9D8) 可用于 WB,ICC/IF,FCM。

Anti-CYP1A2 Antibody (9D8)

Anti-CYP1A2 Antibody (9D8)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04871

Anti-CYP1A2 Antibody (9D8) 是一种 Rabbit 抗体,靶向 CYP1A2。Anti-CYP1A2 Antibody (9D8) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-CYP1A2 Antibody (9D8) is a Rabbit antibody targeting CYP1A2. Anti-CYP1A2 Antibody (9D8) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
9D8
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
组织特异性Liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase).
抗原信息
免疫原
A synthesized peptide: human Cytochrome P450 1A2
抗原种属
Human
基因名称
CYP1A2
基因ID
蛋白名称
Cytochrome P450 1A2
Uniprot ID
功能
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
化学信息
分子量Theoretical: 58 kDa. Actual: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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