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Anti-CYP1A2 Antibody (9D8) 是一种 Rabbit 抗体,靶向 CYP1A2。Anti-CYP1A2 Antibody (9D8) 可用于 WB,ICC/IF,FCM。
Anti-CYP1A2 Antibody (9D8) 是一种 Rabbit 抗体,靶向 CYP1A2。Anti-CYP1A2 Antibody (9D8) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-CYP1A2 Antibody (9D8) is a Rabbit antibody targeting CYP1A2. Anti-CYP1A2 Antibody (9D8) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 9D8 |
| 反应种属 | Human |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| 组织特异性 | Liver. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). |
| 免疫原 | A synthesized peptide: human Cytochrome P450 1A2 |
| 抗原种属 | Human |
| 基因名称 | CYP1A2 |
| 基因ID | |
| 蛋白名称 | Cytochrome P450 1A2 |
| Uniprot ID | |
| 功能 | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. |
| 分子量 | Theoretical: 58 kDa. Actual: 58 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |